Love Berries? 10 Reasons Why You Should Try Lingonberries
Eat lingonberries — the new superfood with exceptional health benefits.
Lingonberries, also known as partridgeberries, redberries or Alaskan lowbush cranberries, grow on an evergreen shrub in northern climates. These berries contain important polyphenols — anthocyanins, resveratrol and quercetin — vitamins — A, C and E — micronutrients — iron and zinc — minerals — manganese, magnesium and potassium — free amino acids and omega-3 fatty acids.
Due to their antioxidant, anticancer, anti-inflammatory and immune-boosting properties, lingonberries are gaining notoriety as a health food.[i],[ii],[iii]  Lingonberries’ most important benefits include fighting cancers, oxidative stress, obesity, metabolic disorders, heart, brain and liver diseases, infections and viruses as well as promoting health and longevity.
1. Fight Cancers
The most successful fractions of lingonberry leaves and fruits against cancer cell lines included proanthocyanidin and quercetin as examined through human in vitro studies of kidney, colon and malignant melanoma cancers.[iv]
Lingonberry extract inhibited the proliferation of liver cancer cells in a dose-dependent manner through in vitro study of human cancer and is believed to be a potential antitumor drug.[v]
Similarly, the effects of 10 different extracts of fruits and berries, including lingonberries, on cell proliferation of colon cancer cells and breast cancer cells in vitro showed significant decreases in both cancers’ growth in a concentration-dependent way.[vi]
A systematic review of 10 lingonberry and 21 bilberry in vitro studies suggested potent inhibition of colorectal cancer cell growth and tumor formation.[vii] Proanthocyanidins — particularly high in blueberries and lingonberries — showed the strongest ability to kill human colorectal cancer cells.[viii]
DARBO CONSERVES Wild Lingonberry Sauce, 14.1 OZ
2. Mediate Oxidative Stress
In a plant study of lingonberry polyphenols, the anthocyanins and flavanols activated the nuclear factor erythroid 2-related factor 2 pathway, scavenged reactive oxygen species and inhibited cellular death — showing its ability to prevent and ameliorate oxidative stress and protect cells.[ix]
In a mice model, a 14-day dose of lingonberry extract prevented acute toxicity from gamma radiation and indicated that lingonberry anthocyanins have immunostimulatory potential against oxidative stress and radiation induced illnesses caused by exposure in medical testing, energy plants and other industries.[x]
In scientific examination of lingonberry compounds, the combination of anthocyanins and copigments possessed the highest antioxidant activities, but all polyphenol fractions protected cells from oxidative stress.[xi]
Through in vitro analysis, total phenolics and flavonoids in lingonberry extracts were slightly higher than those in blueberry extracts but blueberries bested lingonberry in anthocyanin content and antioxidant activity. Both berries were effective against oxidative-stress-related diseases such as cancer, heart, neurological and kidney diseases and arthritis.[xii],[xiii]
3. Protect Heart Health
In an experimental rat model of high blood pressure, long-term treatment with lingonberry juice lowered blood pressure and improved vascular function — two beneficial contributors to heart health — due to its anti-inflammatory properties.[xiv]
Eating lingonberries resulted in decreased triglyceride levels, improved gut microbiome and reduced atherosclerosis in a study of mice for eight weeks.[xv] Lingonberry anthocyanins protected cardiac cells from oxidative-stress-induced apoptosis as studied in vitro.[xvi]
Both lingonberry and blackberry leaves showed strong cardioprotective properties and significantly lowered low-density lipoprotein cholesterol levels associated with cardiovascular disease risk. Results were comparable to lovastatin, a cholesterol-lowering drug.[xvii]
In vitro research suggested that lingonberry’s antioxidant and anti-inflammatory properties may help prevent and treat obesity and corresponding inflammation which can lead to endothelial dysfunction–a coronary artery disease where arteries narrow and interrupt blood flow to the heart.[xviii]
4. Counteract Obesity
Dietary berry fruits — blueberries, cranberries, raspberries, strawberries, mulberries, lingonberries, blackberries, black chokeberries, elderberries, bilberries, grape, blackcurrants, jaboticabas, red bayberries, sea-buckthorns, goldenberries and goji berries — were found to counteract obesity or obesity-associated complications based on animal experiments and human studies.[xix]
Mice fed whole lingonberries showed fewer atherosclerotic plaques, while mice fed the lingonberry fiber fraction had the highest caecal butyric acid — an indicator of gut health. All groups fed lingonberry diets — fiber or berries — had improved plasma lipid profiles.[xx]
5. Prevent Diabetes
In an obese mouse model, mice ate a low-fat, high-fat or lingonberry-supplemented high-fat diet for six weeks. Lingonberries prevented the high-fat diet induced adverse changes in blood cholesterol and glucose levels and had a moderate effect on weight and visceral fat gain — demonstrating its obesity-fighting ability and prevention of comorbidities such as Type 2 diabetes.[xxi]
Mice fed a high-fat diet for eight weeks became obese and insulin-resistant and then were given three different lingonberry extract doses — 125, 250 and 500 milligrams per kilograms (mg/kg) — for eight weeks, which significantly decreased glycemia and insulin levels — Type 2 diabetes markers — in a dose-related way.[xxii]
6. Protect Your Brain
Forty healthy 50- to 70-year-olds drank a mixed berry beverage — 150 grams (g) blueberries, 50 g blackcurrant, 50 g elderberry, 50 g lingonberries, 50 g strawberry and 100 g tomatoes — or a control beverage with no fiber or polyphenols for five weeks.
The berry intervention reduced total and LDL cholesterol, lowered glucose and insulin concentrations and improved memory test performance compared to the baseline and control beverage. Berries showed preventive potential for Type 2 diabetes, cardiovascular disease and cognitive decline.[xxiii]
In a systematic review of blueberries and lingonberries in cell models of neurotoxicity and brain inflammation as well as in vivo models of neurodegenerative diseases, both berries combated reactive oxygen species and showed significant neuroprotective abilities and benefits for brain aging. Surprisingly, the leaves have a much higher antioxidant capacity than the fruits.[xxiv]
Lingonberry extract improved the cognition and memory of mice with cognitive impairment, induced by chronic uncertainty stress, by enhancing the antioxidative ability of tissues and improving the disorder of neurotransmitter levels caused by chronic stress.[xxv]
In an in vitro oxygen-glucose deprived injury rat model, lingonberry significantly protected the brain by suppressing the inflammatory biomarkers in primary neurons and modulating key proteins following hypoxic — when oxygen is lacking in the brain such as in a stroke — injury.[xxvi]
7. Improve the Liver and Kidney
In a high-fat diet-induced obese mouse model, lingonberry supplementation prevented adverse changes in the liver — involving inflammation, and glucose and lipid metabolism — that are known to predispose the development of anonalcoholic fatty liver disease (NAFLD) and its comorbidities.[xxvii]
Polyphenol extracts from arctic berries — lingonberry, alpine bearberry and especially cloudberry — targeted the gut-liver axis and protected against metabolic endotoxemia,[xxviii] insulin resistance and NAFLD in a diet-induced obese mice study.[xxix]
In a mouse model of high fat diet-induced NAFLD, lingonberries inhibited hepatic signaling and improved the liver lipid profile by regulating the expression of genes involved in hepatic lipid metabolism.[xxx]
Eating lingonberries for 12 weeks alleviated high fat diet-induced liver injury in a mouse model by preventing hepatic lipid accumulation, oxidative stress and inflammatory responses.[xxxi] In both animal and in vitro studies, lingonberry treatment demonstrated anti-liver fibrosis activities by increasing antioxidant enzymes.[xxxii]
Taking lingonberry for 12 weeks not only improved high-fat diet-induced renal inflammatory responses but also reduced kidney damage in a mouse model by regulating plasma lipid and glucose profiles and reducing plasma inflammatory cytokine levels.[xxxiii]
8. Regulate Insulin and Glucose
In a study of 20 healthy females consuming either white or rye bread, those who took the 150 g whole-berry purée of strawberries, bilberries, lingonberries and chokeberries had a significantly reduced insulin response.[xxxiv]
In comparison with taking sucrose alone in a study of 20 healthy women, ingestion of sucrose with lingonberries or blackcurrants resulted in reduced glucose and insulin concentrations, slower absorption of glucose and a significantly improved glycemic profile.[xxxv]
9. Prevent Infections and Viruses
Fermented lingonberry juice exerted a positive response in Candida glabrata — the second most common yeast infection — by expressing proteins related to oxidative stress and maintaining cell wall integrity in vitro.[xxxvi]
The extracts of all tested berry fruits, particularly bilberry, strawberry and lingonberry, strongly inhibited coxsackie virus — a marker of Type 1 diabetes — and flu viruses A and H3N2, confirming their antiviral properties.[xxxvii]
Because of the strong effect of lingonberry polyphenols found on oral microbial (viral) load reduction and consequent beneficial respiratory tract anti-inflammatory, antimicrobial and antiviral effects, scientists suggest further research on lingonberries to fight respiratory and coronavirus infections.[xxxviii]
In a comparison study of two berries, lingonberries contained more polyphenols than cranberries but both effectively decreased biofilm formation and oral streptococci activities to prevent dental caries (cavities).[xxxix]
10. Promote Longevity and Healthy Aging
Lingonberries — “superfruits” with the highest content of antioxidants among berries — promote a long life due to their anti-inflammatory, antioxidant, antiviral and anticancer effects.[xl]
Lingonberries both help prevent and treat brain aging and neurodegenerative disorders. In a study of 16,010 patients 70 and older, higher intake of flavonoids, particularly from berries, reduced rates of cognitive decline in older adults.[xli]
Eating lingonberries has a positive influence on healthy aging and promotes longevity.[xlii] Lingonberry seed oil on the skin reduced age spots and eating lingonberries can help fight aging due to their potent vitamin, mineral and polyphenol content.[xliii]
In a study of 99 healthy female subjects taking either a low-dose mix of lingonberry (25 mg) and amla (30 mg) fruit extracts, a double dose of both extracts or a control drink for 12 weeks, significant dose-dependent improvements from the fruit drink in skin elasticity, thickness and hydration as well as the degree of wrinkles showed its antiaging effectiveness.[xliv]
Lingonberries as a Superfood
Why are lingonberries so effective in keeping you healthy? These super berries fight inflammation, which is a key factor in serious illnesses such as cardiovascular disease, cancer, neurological diseases, obesity, diabetes and infectious diseases.[xlv] To learn more, see GreenMedInfo.com’s research on lingonberry and all berries.
References
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[xl] Healthline.com. Nutrition. Lingonberry. https://www.healthline.com/nutrition/lingonberry
[xli] Elizabeth E Devore, Jae Hee Kang, Monique M B Breteler, Francine Grodstein. Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol. 2012 Jul ;72(1):135-43. Epub 2012 Apr 26. PMID: 22535616
[xlii] Katarzyna Kowalska. Lingonberry (L.) Fruit as a Source of Bioactive Compounds with Health-Promoting Effects-A Review. Int J Mol Sci. 2021 May 12 ;22(10). Epub 2021 May 12. PMID: 34066191
[xliii] Facty.com. Food. Nutrition. Lingonberry – The Wonder Berry. https://facty.com/food/nutrition/lingonberry-the-wonder-berry/
[xliv] Uchiyama, T., Tsunenaga, M., Miyanaga, M., Ueda, O. and Ogo, M. (2019), Oral intake of lingonberry and amla fruit extract improves skin conditions in healthy female subjects: A randomized, double-blind, placebo-controlled clinical trial. Biotechnology and Applied Biochemistry, 66: 870-879. https://doi.org/10.1002/bab.1800
[xlv] Yale Medicine. How Inflammation Affects Your Health. https://www.yalemedicine.org/news/how-inflammation-affects-your-health
Dr. Diane Fulton is Emeritus Professor at Clayton State University. She holds Ph.D./MBA in Business (University of Tennessee – Knoxville) and B.S. with Math/Secondary Education majors (University of Wisconsin – Milwaukee). During her 45-year career as administrator/professor teaching research and business, she authored 10 books, over 50 articles, and is now writing children’s books about the body, mindfulness and cross-cultural awareness. Her passion is to share her knowledge to integrate a healthy body, mind and soul. To reach her: Clayton University’s Emeritus Professors Diane Fulton LINKED IN or Diane Fulton FACEBOOK.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of GreenMedInfo or its staff.
Source: GreenMedInfo
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