Revisiting Depression — Dopamine-Serotonin Balance Gains Attention for Treatment-Resistant Depression
Story at-a-glance A major clinical trial in The Lancet Psychiatry found that boosting dopamine with pramipexole improved symptoms in treatment-resistant depression. This challenges the long-dominant serotonin deficiency theory Supporting those findings, another study showed that agomelatine, a serotonin-blocking drug, consistently reduced anxiety and depression in…

